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Provigate received STS grant from NEDO.

Development of a tear fluid clinical testing platform.

Provigate’s proposal has been selected by the New Energy and Industrial Technology Development Organisation (commonly known as NEDO) under the “Commercialisation Support Grant for R&D Ventures in the Seed Phase” (commonly known as NEDO-STS).
The proposed project aims to build a platform for testing various biomarkers of tear fluid by converting our patented tear sugar biotransistor technology.
Specifically, we will develop a kit that enables anyone to collect tear fluid safely and easily and a system that can stably and easily detect and quantify the target low-concentration biomarkers from a very small sample of tear fluid.
The project period is scheduled from the date of the grant decision to 28 February 2017.

People may think of glucose monitoring as simple as this: "Diabetes is a disease of blood sugar. This is why people with diabetes use glucometer."
However, it's not that simple. Blood sugar measurement has diverse objectives, including diagnosing diabetes, dosing self-injection of insulin, avoiding hypoglycemia due to excessive drug efficacy, and behavior change.
You must choose the appropriate blood sugar measurement method for your purpose.

There are two types of self-blood glucose measurement methods: SMBG (Self-Monitoring of Blood Glucose), which is widely used, and CGM (Continuous Glucose Monitoring), which has become popular in recent years.
These two blood glucose measurement methods are designed mainly for patients who self-inject insulin and other injectable drugs.
Until now, there has been no simple and daily method for measuring blood glucose at home other than these two methods.

Some drugs, such as insulin, are very potent and can cause dangerous hypoglycemia if the dosage is incorrect.
Therefore, for example, those who use insulin must measure their blood glucose accurately before self-injection at home and carefully determine the dose.
After injection, if there are signs of hypoglycemia, it is necessary to measure blood glucose immediately. If necessary, you need to take some sugar to avoid hypoglycemia.
However, both methods have an issue with invasiveness. In addition, they cost a lot. CGM costs at least $60 and needs to be replaced every two weeks, which is also a significant economic burden. SMBG requires frequent measurements, so the total cost becomes significant when accumulated.
Unfortunately, SMBG and CGM are not suitable for everyone due to invasiveness and cost.



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